Piyush Arora1, Himanshu Mittal2, Neeraj Gupta3, Jose K. Jimmy4 Khushboo Jain5 Arpit Sharma6
BACKGROUND
Covid-2019, caused by severe acute respiratory syndrome-coronavirus-2 (SARS
CoV2), is an ongoing pandemic that emerged from China in November 2019. It
has affected millions of people worldwide causing significant morbidity and
mortality. We wanted to analyse the clinical and demographic profile of Covid-19
patients admitted in a tertiary-care-centre in the central part of Rajasthan,
compare their characteristics with other studies published from parts of Northern-
India and identify factors associated with delayed recovery and mortality.
METHODS
This was a retrospective observational analysis of the clinical features, and
epidemiological profile of Covid-19 positive patients admitted at a tertiary-carecentre
in the Central part of Rajasthan.
RESULTS
A total of 422 patients was enrolled in the study. The male: female ratio was 1.34
with a mean age of 34.1 years. Almost 195 (46.2 %) patients were in the age
group of 20 - 40 years. Respiratory diseases were the most common co-morbidity
seen in 36 patients (8.53 %), diabetes-mellitus in 28 patients (6.63 %),
hypertension in 22 patients (5.2 %). Fever was the commonest presenting
symptom (N = 98, 77.17 %), followed by cough (N = 85, 66.93 %), and
breathlessness (N = 51, 45.67 %). Factors significantly associated with mortality
were age group of 60 - 80 year (P < 0.001), presence of co-morbidities (P < 0.001)
and history of smoking & alcohol consumption (P < 0.001). Among co-morbidities
diabetes-mellitus, hypertension, chronic-respiratory-diseases & chronic-kidneydiseases
had significant impact on mortality. Absence of co-morbidity, lack of
addiction and symptoms at the time of presentation were associated with an
earlier conversion of reverse transcription polymerase chain reaction (RT-PCR)
report.
CONCLUSIONS
Clinical spectrum of COVID 19 varies widely. Presence of comorbidities, addiction,
radiological features has a drastic impact on mortality and duration of infectivity.
