STUDY OF CLINICAL PRESENTATIONS OF PATIENTS WITH HYPERPROLACTINAEMIA VISITING A TERTIARY CARE HOSPITAL

Abstract

Binoy Kumar Mohanty1, Arun Kumar Choudhury2, Anoj Kumar Baliarsinha3

BACKGROUND
Hyperprolactinaemia is one of the common endocrine disorders seen in clinical practice. It may result due to various causes and elucidating the exact cause is necessary to formulate the right therapy.
OBJECTIVE
To study the various aetiologies and clinical presentation of patients presenting with hyperprolactinaemia to a tertiary care hospital.
DESIGN
Cross-sectional study.
MATERIAL AND METHODS
We collected and analysed the clinical data including hormonal status of 74 consecutive patients who presented to our department from June 2015 to May 2016 for evaluation of hyperprolactinaemia.
RESULTS
Majority of the subjects studied belonged to 20-29 years group (47.29%) followed by 30-39 years age group (24.32%). The most common cause in our population was due to drug-induced causes (35.13%). The next common causes included idiopathic group (20.4%) followed by pituitary adenomas (16.21%). There was significant female predominance (83.78%) among total cases. Among women who presented with hyperprolactinaemia, menstrual irregularity (69.35%) followed by galactorrhoea (35.48%) were the most common presentations.
CONCLUSIONS
Hyperprolactinaemia is frequently seen among women who presented with either menstrual irregularity or galactorrhoea or both. Drug-induced hyperprolactinaemia is the most common cause seen in our study population.

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