STUDY OF EVALUATION OF RISK FACTORS OF ACUTE MYOCARDIAL INFARCTION WITH SPECIAL REFERENCE TO VITAMIN D STATUS- A CASE CONTROL STUDY, DONE AT A TERTIARY CARE HOSPITAL OF TRIPURA

Abstract

Arunabha Dasgupta, Mrinal Debbarma, Chinmoy Biswas

BACKGROUND Acute Myocardial Infarction (AMI) is a leading cause of morbidity and mortality globally. Efforts are always there to identify predisposing risk factors associated with development of AMI so that preventive approaches can be adopted for therapeutic interventions or life style changes. This study was conceptualized to identify the responsible risk factors with AMI & to evaluate their power of association. An approach was also adopted to identify whether co-existence of deficiency of vitamin D (25(OH) D) along with the classic risk factors further endangers the population. The objectives of the study were- 1) To identify risk factors of AMI & to evaluate their power of association. 2) To estimate vitamin D level in all cases and controls and to study statistical correlation of vitamin D with classic risk factors. MATERIALS AND METHODS It is a case control study, where 130 cases of AMI & 130 healthy controls from patient’s attendants were included. Patients were evaluated clinically, and investigations were done to identify the classic risk factors. Simultaneously vitamin D (25(OH) D) level was estimated in all cases and controls. Results obtained were analysed statistically to evaluate the power of association of the risk factors. The statistical package for social science version 16 IBM Corporation was used for statistical analysis and P Value of <0.05 was considered significant.

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