STUDY OF IDIOPATHIC CALCIUM NEPHROLITHIASIS AND VITAMIN D DEFICIENCY

Abstract

Rajan S. P. 1 , Santhosh 2 , Lavanya Madhavan 3

BACKGROUND Vitamin D deficiency is a worldwide health concern. It prevails in epidemic proportions all over the Indian subcontinent with a prevalence of 70%-100% in the general population. Vitamin D is important in maintaining calcium and phosphorus homeostasis, but its role in kidney stone disease and its effect on stone formation are still not clear. AIMS AND OBJECTIVES In the present study, association between levels of Vitamin D and nephrolithiasis were studied. MATERIALS AND METHODS 50 patients with nephrolithiasis were selected and were compared with 50 controls matched in terms of age and sex. 25-OH Vitamin D levels were measured in both groups. RESULTS 25-OH Vitamin D levels were low in patients with nephrolithiasis when compared to controls.

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