Ganeswar Sethy1, Abinash Swain2, Abinash Panda3, Geetanjali Sethy4
BACKGROUND
Dengue is an acute viral haemorrhagic fever with large number of fatalities
worldwide. According to WHO, 50 - 100 million infections occur annually, out of
which 5 lakhs are dengue haemorrhagic fever. India is no way better like any other
tropical country. Southern part of Odisha shows high prevalence of dengue cases
which are referred to MKCG Medical College, Berhampur. Dengue is a vector borne
disease, which is of much epidemiological importance throughout India. No clinical
study has been undertaken in recent past on this disease as regard to clinical
parameter, course and outcome. Hence, it was decided to carry out a study to
assess the epidemiological profile of dengue patients, the prevalence and pattern
of liver and kidney dysfunction and outcome of hospitalized patients in MKCG
Medical College and Hospital.
METHODS
This cross-sectional study was carried out on laboratory confirmed dengue patients
admitted to hospital in Department of Medicine, MKCG Medical College & Hospital,
Berhampur from January 2018 to December 2018.
RESULTS
More number of patients (58 %) were male and from rural area (72 %). Alanine
aminotransferase (ALT) and aspartate aminotransaminase (AST) were elevated in
68 % of cases to more than 3 times of normal. Mortality is 4 % among the admitted
patient. More death observed with high international normalized ratio (INR) value.
CONCLUSIONS
Mortality is high in patients of dengue with deranged liver function and kidney
function. Early screening of dengue patients by clinical and laboratory parameter
will help clinicians to predict mortality for dengue cases. Dengue cases with liver
and kidney dysfunction need aggressive monitoring and appropriate management
to prevent complications and death.
