STUDY OF PREOPERATIVE SERUM BILIRUBIN AND SERUM C-REACTIVE PROTEIN WITH POSTOPERATIVE HISTOPATHOLOGY IN DIAGNOSIS OF ACUTE APPENDICITIS

Abstract

Trishul Senapati Aakala1, Charan Panda2, Suramya Anand3, Manas Ranjan Behera4, Chitta Ranjan Thatei5

BACKGROUND
Delayed or wrong diagnosis of acute appendicitis in patients results in complications like perforation, gangrene, etc. These complications carry a significant amount of morbidity and mortality to the patients. So timely diagnosis of acute appendicitis by the surgeon plays an important role to prevent these complications. Recently, it was found that serum bilirubin and serum C-reactive protein (CRP) individually can be a useful marker for appendiceal perforation/gangrene. In this era of technical edge, some places specifically in this part of world, people lack this technological advantage (i.e. access to ultrasonography), so simple laboratory investigation can be very useful for the surgeon regarding diagnosis point of view.
METHODS
Here in this retrospective study, 100 patients were included randomly during September 2013 to August 2015, suffering from acute pain abdomen suspecting clinically as acute appendicitis and got admitted to Department of General Surgery of MKCG Medical College, Berhampur, Odisha for the treatment of same.
RESULTS
During management of those patients, the intraoperative finding was noted, which latter confirmed by histopathological finding, are compared with preoperative blood investigation (i.e. serum bilirubin and serum CRP). The findings are noted and analysed and tried to find the relationship of serum bilirubin and serum CRP with acute appendicitis.
CONCLUSION
We will try to see how helpful the above obtained results are and thus their importance regarding the diagnosis of the same for the surgeon.

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