Kalinga B.E.1 , Shruthi C. Bhojashettar2 , Salman Beig3 , Niranjan M.4
BACKGROUND The metabolic dysregulation associated with DM causes secondary pathophysiological changes in multiple organ systems. We wanted to estimate the levels of serum magnesium and HbA1c in type 2 diabetes mellitus patients, study the correlation between serum magnesium and glycaemic control in these patients and evaluate the relation between serum magnesium and duration of diabetes in patients with type 2 diabetes mellitus. METHODS This is a cross sectional study of 160 cases conducted during between February 2017 to September 2018, in KIMS Hospital Hubli. RESULTS Out of 160 cases, 42% had hypomagnesemia whereas only 3% of the control group had low levels of magnesium. Mean value of magnesium was found to be lower in patients with diabetes of duration >10 years (1.4 mg/dL), whereas magnesium mean value was 2.1 mg/dL in patients with diabetes duration <5 years. Study results showed significant negative correlation between HbA1c, FBS, PPBS and serum magnesium. Mean magnesium level in the study group with HbA1c of more than 10 and less than 8 was 1.2 mg/dL and 2.0 mg/dL respectively. Magnesium levels were comparatively low in patients who were on insulin therapy. CONCLUSIONS Hypomagnesemia was more common in diabetes patients, especially in patients with longer duration of the disease. Lower magnesium levels were associated with poorer glycaemic control.
