Ravinder Pal Singh1 , Rajan Goyal2 , Nitin Kumar Gupta3 , Prerna4 , Abhinav Kumar5
BACKGROUND Patients with DM are at increased risk of thyroid disease, especially those with poor glycaemic control. The following mechanisms are thought to be responsible. In patients with DM, the nocturnal TSH peak is blunted or abolished; the TSH response to TRH, from the hypothalamus, is impaired thus leading to hypothyroidism. We wanted to study the thyroid disorders in type 2 diabetic and non-diabetic patients attending a tertiary care hospital. METHODS This is an analytical observational study conducted among 100 type 2 diabetic and 100 non-diabetic patients attending medicine OPD in the Department of General Medicine of Narayan Medical College & Hospital, Jamuhar, Distt. Rohtas over a 6- month period from Oct 2019 to April 2020. RESULTS The mean age of group A and group B was found to be 51.79 ± 10.374 and 49.86 ± 9.538 respectively. In group A (diabetes mellitus patients), 71 (71 %) patients were euthyroid whereas in group B (healthy individuals) 84 (84 %) patients were euthyroid. In Group A (diabetes mellitus group) either subclinical or overt hypothyroidism was seen in 26 (26 %) patients and hyperthyroidism was seen in 3 (3 %) patients. In Group B (healthy individuals) either subclinical or overt hypothyroidism was seen in 14 (14 %) patients and hyperthyroidism was seen in 2 (2 %) patients. CONCLUSIONS The comparison of the patients of control and cases groups on the basis of whether they had a normal or abnormal thyroid function test showed that patients with diabetes mellitus type 2 (Group A) were more likely to be having abnormal thyroid function test as compared to healthy individuals (Group B) and this difference was found to be statistically significant (p = 0.027).
