Dr. Shobha Rani Chakrawarty,
BACKGROUND Sickle cell disease is a worldwide health problem and is the most common inherited haemoglobinopathy. Patients with sickle cell Disease have increased rates of maternal and foetal complications compared to general population. A particularly serious complication of sickle cell disease is high blood pressure in the blood vessels that supply the lungs. This disease, which is present in affected individuals at birth, causes production of abnormal haemoglobin. Early diagnosis and regular medical care are essential to prevent complications and also to improve well-being. The main objective is to study the foetal and maternal outcome in sickle cell disease. METHODS The study was conducted in the department of obstetrics and gynaecology of LTBRKM Gov. Medical College, Jagdalpur Chhattisgarh. The study was carried out from Dec 2018 to May 2019. The study included all patients attending antenatal clinic with sickle cell disease. 51 patients were included in the study. The obtained data was compiled, analysed and interpreted. Data was analysed through SPSS. Permission from Institutional Ethics Committee was obtained. RESULTS Still birth and neonatal death rate was 5.33%. Cause of neonatal death was septicaemia. In still birth group, all cases were of foetal demise on admission. In HbAS group 56% of patients delivered vaginally, 39% of patients required lower segment caesarean section. In HbSS group, 45% of patients delivered vaginally and also same %age of patient underwent LSCS. CONCLUSIONS There is a need to screen mothers who are with sickle cell disease. Early and regular prenatal care is important for pregnant women with sickle cell disease to prevent complications of sickle cell disease.
